LONDON (AP)—The World Health Organization (WHO) declared Wednesday that the increasing spread of mpox in Africa is a global health emergency and warned that the virus might ultimately spill across international borders.
The announcement by WHO Director-General Tedros Adhanom Ghebreyesus came after a meeting of the U.N. health agency’s emergency committee. The Africa Centers for Disease Control and Prevention (CDC) declared mpox a public health emergency on the continent on Tuesday, August 13.
WHO said there have been more than 14,000 cases and 524 deaths in Africa this year, already exceeding last year’s figures. So far, more than 96% of all cases and deaths are in a single country: Congo. Scientists are concerned by the spread of a new version of the disease there that might be more easily transmitted among people.
Here’s what is currently known about mpox, and what might be done to contain it.
What is mpox?
Mpox, also known as monkeypox, was first identified by scientists in 1958, when there were outbreaks of a “pox-like” disease in monkeys.
Until recently, most human cases were seen in people in central and West Africa who had close contact with infected animals. In 2022, the virus was confirmed to spread via sex for the first time and triggered outbreaks in more than 70 countries across the world that had not previously reported mpox.
Mpox belongs to the same family of viruses as smallpox, but causes milder symptoms like fever, chills, and body aches. People with more serious cases can develop lesions on the face, hands, chest, and genitals.
What’s happening in Africa that’s causing this concern?
The number of mpox cases in Africa has jumped dramatically. Last week, the Africa CDC reported that mpox has now been detected in at least 13 African countries. Compared with the same period last year, the agency said cases are up 160% and deaths have increased by 19%.
Earlier this year, scientists reported the emergence of a new form of mpox in a Congolese mining town that can kill up to 10% of people and might spread more easily. Unlike in previous mpox outbreaks, where lesions were mostly seen on the chest, hands, and feet, the new form of mpox causes milder symptoms and lesions on the genitals. That makes it harder to spot, meaning people might also sicken others without knowing they’re infected themselves.
WHO said mpox was recently identified for the first time in four East African countries: Burundi, Kenya, Rwanda, and Uganda. All of those outbreaks were linked to the epidemic in Congo. Tedros said there was concern about the further spread of the disease in Africa and beyond.
In the Ivory Coast and South Africa, health authorities have reported outbreaks of a different and less dangerous version of mpox that spread worldwide in 2022.
What does an emergency declaration mean?
WHO’s emergency declaration is meant to spur donor agencies and countries into action, but the global response to previous declarations has been mixed.
Africa CDC Director General Dr. Jean Kaseya said the agency’s declaration of a public health emergency was meant “to mobilize our institutions, our collective will, and our resources to act swiftly and decisively.” He appealed to Africa’s international partners for help, saying the escalating caseload in Africa had largely been ignored.
“It’s clear that current control strategies aren’t working and there is a clear need for more resources,” said Michael Marks, a professor of medicine at the London (UK) School of Hygiene and Tropical Medicine. “If a (global emergency declaration) is the mechanism to unlock these things, then it is warranted.”
What’s different about the current outbreak in Africa compared to the 2022 epidemic?
During the global outbreak of mpox in 2022, gay and bisexual men made up the vast majority of cases and the virus was mostly spread through close contact, including sex. Although some similar patterns have been seen in Africa, children under 15 now account for more than 70% of the mpox cases and 85% of deaths in Congo.
Before itthes emergency meeting, Tedros said officials were dealing with several mpox outbreaks in various countries with “different modes of transmission and different levels of risk.”
“Stopping these outbreaks will require a tailored and comprehensive response,” he said.
Greg Ramm, Save the Children’s Congo director, said that organization was particularly worried about the spread of mpox in the crowded camps for refugees in the east, noting 345,000 children were “crammed into tents in unsanitary conditions” whenthe country’s health system was already “collapsing” under the strain of malnutrition, measles, and cholera.
Dr. Boghuma Titanji, an infectious diseases expert at Emory University, said it was unclear why children were so disproportionately hit by mpox in Congo. She said it might be because kids are more susceptible to the virus or that social factors, such as overcrowding and exposure to parents who caught the disease, might explain it.
How might mpox be stopped?
The 2022 outbreak of mpox in dozens of countries was largely shut down with the use of vaccines and treatments in rich countries, in addition to convincing people to avoid risky behavior, but barely any vaccines or treatments have been available in Africa.
Marks said that immunization would probably help—including inoculating people against smallpox, a related virus. “We need a large supply of vaccine so that we can vaccinate populations most at risk,” he said. That would mean sex workers, children, and adults living in outbreak regions.
Officials in Congo have said it’s in talks with donors about possible vaccine donations and has gotten some financial aid from Britain and the U.S. WHO had already released $1.45 million from its emergency fund to support the response to mpox in Africa, but said it needs an initial $15 million to fund that response.
___
Associated Press writer Christina Malkia in Kinshasa, Congo, contributed to this report.
___
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.